This sounds like a fine way to fight colds. From Igor Chudov at igor-chudov.com:
Also a marked increase in immune deficiency
A new mRNA vaccine is being developed: Moderna’s mRNA-1345 is a proposed immunization against RSV, one of the viruses causing colds in adults. Clinical trial results were published in the New England Journal of Medicine today.
https://www.nejm.org/doi/full/10.1056/NEJMoa2307079?query=TOC
The clinical trial’s 35,541 participants were assigned to receive the mRNA-1345 vaccine (17,793 participants) or placebo (17,748). (The placebo was saline.)
Moderna proudly reported that its RSV vaccine prevented 66 cases of RSV in 17 thousand vaccinated people. Per the appendix:
The Moderna study explains:
Vaccine efficacy was 68.4% (95% CI, 50.9 to 79.7) against RSV-associated acute respiratory disease. Protection was observed against both RSV subtypes (A and B) and was generally consistent across subgroups defined according to age and coexisting conditions.
mRNA RSV vaccine efficacy of just 68% was relatively meager, far worse than the much-ballyhooed “95% efficacy” of COVID vaccines.
