Tag Archives: Ivermectin

Pfizer Launches Final Study For COVID Drug That’s Suspiciously Similar To ‘Horse Paste’, by Tyler Durden

Imitation is the sincerest form of flattery. From Tyler Durden at zerohedge.com:

Another piece US anti-Ivermectin puzzle may have emerged. On Monday, Pfizer announced that it’s launching an accelerated Phase 2/3 trial for a COVID prophylactic pill designed to ward off COVID in those may have come in contact with the disease.

Coincidentally (or not), Pfizer’s drug shares at least one mechanism of action as Ivermectin – an anti-parasitic used in humans for decades, which functions as a protease inhibitor against Covid-19, which researchers speculate “could be the biophysical basis behind its antiviral efficiency.”

Lo and behold, Pfizer’s new drug – which some have jokingly dubbed “Pfizermectin,” is described by the pharmaceutical giant as a “potent protease inhibitor.”

As Zero Hedge readers might recognize, that’s exactly what ivermectin, the prophylactic used for a number of reasons in both humans and animals, does. And unlike Pfizer’s experimental drug, ivermectin already may have saved hundreds of thousands of lives from India to Brazil.

We aren’t the only ones to have put this together, as twitter users have commented on the similarities. The timing – which coincides with the whole “horse dewormer” smear campaign – just seems odd.

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MSN Showcases the Amazing Uttar Pradesh Turnaround–The Ivermectin-based Home Medicine Kits, by TrialSite Staff

It’s hard to write off the experiences of 230 million people as “anecdotal.” From the TrialSite Staff at trialsitenews.com:

Recently Indian press touted that Uttar Pradesh, India’s most populous state with about 230 million people was nearly COVID-19 free. An amazing accomplishment chronicled by TrialSite—a heroic public health story demonstrating how organized, proactive testing, early care, and quarantines contributed to overcoming an outright scary Delta variant-based surge from April to May of this year. The proactive use of Ivermectin, included in a home health care kit, showed to be instrumental in combating the incredibly virulent and transmissible strain of SARS-CoV-2. Public health workers made continuous visits to homes in villages and districts across the state, proactively testing and treating the condition immediately, including household contacts. Even the World Health Organization (WHO) praised the effort, yet omitted the use of Ivermectin—a scandal. Now Microsoft News (MSN) posted the story for the world to read, digest and hopefully understand.

MSN appears to be the first mainstream news source to recognize the amazing feat accomplished by the health agencies in India’s most populous state. The state experienced a massive spike in infections by April, but just two months later, the turnaround was well on its way, and what ensued should have been the story of the year.

The Outbreak

TrialSite provided in detail data associated with the Delta outbreak in India. The Delta variant of concern emerged from the State of Maharashtra and the Punjab regions by way of Lahore in Pakistan, locations where the AstraZeneca vaccine had been administered. Maps associated with the first outbreaks can be found here. Any correlation with vaccination, however, cannot be proven and may be coincidental.

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Horowitz: Heavily vaccinated state accounts for 65% of India’s COVID cases after rejecting ivermectin

This is just not supposed to be happening. Consequently, most people aren’t going to hear about it. From Daniel Horowitz at theblaze.com:

The Indian state of Kerala has 3% of India’s population, and 67% of its inhabitants have at least one vaccination. One would expect Kerala’s COVID cases to be so low as to be invisible in a chart of India’s very low overall cases. Yet this state of just 33 million people accounted for 65% of all of India’s cases on Thursday, and even more in recent weeks. It has essentially been the only state experiencing a surge in recent months. It also happens to be the Indian state that has rejected ivermectin.

I have written several columns on the miracle of Uttar Pradesh, India’s largest state, which has essentially eradicated COVID with the universal use of ivermectin. In general, most of India experienced very few COVID cases since the large spring wave because there is a great deal of immunity built up. However, Uttar Pradesh, despite its population of 240 million people, has been averaging fewer than 20 cases over the past few months for its seven-day rolling average.

This is India at large:

Now compare to Uttar Pradesh, which has a flat line rather than just a low churn.

Now let’s compare this to the state of Kerala, which has removed ivermectin and other proven therapeutics from its treatment protocol and has gone all in on the ineffective remdesivir.

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Ivermectin for COVID-19: real-time meta analysis of 63 studies

For those who insist on science, from ivmmeta.com h/t Bil:

Covid Analysis, Sep 14, 2021, Version 118discussion updates (V1 Nov 26, 2020)  [GMK response, Elgazzar

Meta analysis using the most serious outcome reported shows 69% [54‑79%] and 86% [75‑92%] improvement for early treatment and prophylaxis, with similar results after exclusion based sensitivity analysis and restriction to peer-reviewed studies or Randomized Controlled Trials.
Statistically significant improvements are seen for mortality, hospitalization, recovery, cases, and viral clearance. 29 studies show statistically significant improvements in isolation.
Studies Prophylaxis Early treatment Late treatment Patients Authors
All studies 63 86% [75‑92%] 69% [54‑79%] 40% [24‑52%] 26,422 623
Peer-reviewed 45 86% [74‑93%] 70% [52‑81%] 43% [21‑59%] 17,316 490
Randomized Controlled Trials 31 84% [25‑96%] 64% [48‑74%] 30% [2‑50%] 6,561 369
Percentage improvement with ivermectin treatment
There is evidence of a negative publication bias, and the probability that an ineffective treatment generated results as positive as the 63 studies is estimated to be 1 in 1 trillion.
While many treatments have some level of efficacy, they do not replace vaccines and other measures to avoid infection. Only 27% of ivermectin studies show zero events in the treatment arm.
Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. All practical, effective, and safe means should be used. Those denying the efficacy of treatments share responsibility for the increased risk of COVID-19 becoming endemic; and the increased mortality, morbidity, and collateral damage.
The evidence base is much larger and has much lower conflict of interest than typically used to approve drugs.
All data to reproduce this paper and sources are in the appendix. See [Bryant, Hariyanto, Kory, Lawrie, Nardelli] for other meta analyses with similar results confirming efficacy.

00.250.50.7511.251.51.752+Kory et al.69%0.31 [0.20-0.47]Improvement, RR [CI]Bryant et al.62%0.38 [0.19-0.73]Lawrie et al.83%0.17 [0.08-0.35]Nardelli et al.79%0.21 [0.11-0.36]Hariyanto et al.69%0.31 [0.15-0.62]WHO (OR)81%0.19 [0.09-0.36]ivmmeta58%0.42 [0.30-0.59]Ivermectin meta analysis mortality resultsivmmeta.com Sep 14, 2021Lower Risk

Evidence base used for other COVID-19 approvals
Medication Studies Patients Improvement
Budesonide (UK) 1 1,779 17%
Remdesivir (USA) 1 1,063 31%
Casiri/imdevimab (USA) 1 799 66%
Ivermectin evidence 63 26,398 67% [59‑74%]
A

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The Immorality of Ignoring Ivermectin, by Parker Beauregard

How can a medical profession that is charged with doing all within its power to improve health and save lives ignore a Covid remedy that is safe and has been proven effective both anecdotally and in randomized and controlled trials? From Parker Beauregard at thebluestateconservative.com:

“While this court is sympathetic to the Plaintiff and understands the idea of wanting to do anything to help her loved one, public policy should not and does not support allowing a physician to try ‘any’ type of treatment on human beings.”

This was the stated decision by an Ohio judge on September 6th in response to experimental Covid treatments being administered to a hospital patient. Now, someone waking up from a coma might interpret this pronouncement as an end to vaccine mandates, and indeed most messaging around Covid vaccination in general. They would have good reason to suspect as much. After all, by the judge’s own logic, “public policy should not and does not support allowing a physician to try any type of treatment on human beings.” If an experimental, gene-altering vaccine that was rushed through production and approval does not qualify as “any type of treatment,” then what would?

Tragically, the judge’s did not relate to experimental and unproven vaccines; instead, it referred to the denial of a fifty-year-old generic drug with a proven safety record as a potential Covid therapeutic.

Judges in Ohio, unfortunately, are far from the only evil creatures wading into medical malpractice. Throughout the pandemic, mainstream media and political string-pullers have attempted to further discredit the phenomenal success of Ivermectin in places as diverse and far ranging as Buenos Aires, Mexico City, Peru, India, and elsewhere. Courageous doctors at America’s Frontline Doctors and Frontline Covid-19 Critical Care Alliance have developed successful treatment protocols,  who are at best are ignored, and at worst demonized, by the likes of corrupt individuals like Anthony Fauci and corrupt organizations like the CDC.

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Why all the fuss about Ivermectin? by Brian C. Joondeph

Like just about all drugs, Ivermectin can be dangerous and lethal if it is misused. Like many human drugs, it is also used on animals. So what? From Brian C. Joondeph at americanthinker.com:

First hydroxychloroquine, now ivermectin, is the hated deadly drug de jour, castigated by the medical establishment and regulatory authorities. Both drugs have been around for a long time as FDA-approved prescription medications. Yet now we are told they are as deadly as arsenic.

As a physician, I am certainly aware of ivermectin but don’t recall ever writing a prescription for it in my 30+ years’ medical career. Ivermectin is an anthelmintic, meaning it cures parasitic infections. In my world of ophthalmology, it is used on occasion for rare parasitic or worm infections in the eye.

Ivermectin was FDA approved in 1998 under the brand name Stromectol, produced by pharmaceutical giant Merck, approved for several parasitic infections. The product label described it as having a “unique mode of action,” which “leads to an increase in the permeability of the cell membrane to chloride ions.” This suggests that ivermectin acts as an ionophore, making cell membranes permeable to ions that enter the cell for therapeutic effect.

Ivermectin is one of several ionophores, others including hydroxychloroquine, quercetin, and resveratrol, the latter two available over the counter. These ionophores simply open a cellular door, allowing zinc to enter the cell, where it then interferes with viral replication, providing potential therapeutic benefit in viral and other infections.

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Rolling Stone Issues ‘Update’ After Horse Dewormer Hit-Piece Debunked, by Tyler Durden

Rolling Stone published a one-source story from a guy who basically made it up out of whole cloth. Rolling Stone apparently did not check the story’s veracity. Is it any wonder people turn to the alternative media? From Tyler Durden at zerohedge.com:

Update (1155ET): Rolling Stone has issued an ‘update,’ not a correction, or a retraction, by appending the hospital’s statement to the top of the article.

*  *  *

After Joe Rogan announced that he’d kicked Covid in just a few days using a cocktail of drugs, including Ivermectin – an anti-parasitic prescribed for humans for over 35 years, with over 4 billion doses administered (and most recently as a Covid-19 treatment), the left quickly started mocking Rogan for having taken a ‘horse dewormer’ due to its dual use in livestock.

Rolling Stone’s Jon Blistein led the charge:

On Friday, Rolling Stone‘s Peter Wade took another stab – publishing a hit piece claiming that Oklahoma ERs were overflowing with people ‘overdosing on horse dewormer.’

It was suspect from the beginning.

The report, sourced to local Oaklahoma outlet KFOR‘s Katelyn Ogle, cites Oklahoma ER doctor Dr. Jason McElyea – who claimed that people overdosing on ivermectin horse dewormer are causing emergency rooms to be “so backed up that gunshot victims were having hard times getting” access to health facilities.

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Ivermectin in Africa Blocks Covid, by Paul Craig Roberts

Sometimes one graph is worth a gazillion, gazillion words. From Paul Craig Roberts at paulcraigroberts.org:

I suppose Fauci will say Ivermectin only works for blacks.

The Triumph of Evil, by Paul Craig Roberts

The campaign to suppress Ivermectin amounts to sanctioned murder. From Paul Craig Roberts at paulcraigroberts.com:

The West’s Medical Authorities and Presstitute Media Should be Indicted for Conspiracy to Commit Mass Murder

Ohio Judge Orders Hospital To Treat Ventilated COVID-19 Patient With Ivermectin

https://www.zerohedge.com/markets/ohio-judge-orders-hospital-treat-ventilated-covid-19-patient-ivermectin?utm_campaign=&utm_content=Zerohedge%3A+The+Durden+Dispatch&utm_medium=email&utm_source=zh_newsletter

The murderers at West Chester Hospital in Cincinnati would rather patients die than to treat them with Ivermectin.  This is how crazed and brainwashed the Medical establishment is. A judge had to intervene to force the hospital to give Ivermectin treatment to a dying patient.  In America to get competent medical treatment requires wining a court case.

The corrupt public health authorities protecting Big Pharma profits use the excuse that people desperate for Ivermectin but unable to get Ivermectin for humans are harming themselves by taking large doses in formulations for animals.  This, of course, is not a justification for banning the use of doses formulated for people.

Ivermectin Suppressed Covid in Africa where it is used against River Blindness

In an earlier article I pointed out that in malaria-infested countries where the population has traditionally taken HCQ weekly to ward off infection,  Covid cases are rare as HCQ is also a covid preventative and cure.

Now evidence arises from  Japanese researchers that in countries in Africa where Onchocerciasis or River Blindness is endemic, Ivermectin is distributed to the population to prevent or cure infection.  In these countries, there is practically no Covid.

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Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations, by Andy Crump

Ivermectin is a wonder drug, and the campaign to keep it from people as remedy for Covid is criminal. From Andy Crump at nature.com:

Abstract

Over the past decade, the global scientific community have begun to recognize the unmatched value of an extraordinary drug, ivermectin, that originates from a single microbe unearthed from soil in Japan. Work on ivermectin has seen its discoverer, Satoshi Ōmura, of Tokyo’s prestigious Kitasato Institute, receive the 2014 Gairdner Global Health Award and the 2015 Nobel Prize in Physiology or Medicine, which he shared with a collaborating partner in the discovery and development of the drug, William Campbell of Merck & Co. Incorporated. Today, ivermectin is continuing to surprise and excite scientists, offering more and more promise to help improve global public health by treating a diverse range of diseases, with its unexpected potential as an antibacterial, antiviral and anti-cancer agent being particularly extraordinary.

Introduction

The unique and extraordinary microorganism that produces the avermectins (from which ivermectin is derived) was discovered by Ōmura in 1973 (Figure 1). It was sent to Merck laboratories to be run through a specialized screen for anthelmintics in 1974 and the avermectins were found and named in 1975. The safer and more effective derivative, ivermectin, was subsequently commercialized, entering the veterinary, agricultural and aquaculture markets in 1981. The drug’s potential in human health was confirmed a few years later and it was registered in 1987 and immediately provided free of charge (branded as Mectizan)—‘as much as needed for as long as needed’—with the goal of helping to control Onchocerciasis (also known as River Blindness) among poverty-stricken populations throughout the tropics. Uses of donated ivermectin to tackle other so-called ‘neglected tropical diseases’ soon followed, while commercially available products were introduced for the treatment of other human diseases.

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