Tag Archives: Immune escape

Omicron Variant and Vaccine Resistance, by Joseph Mercola

Not that people should panic, but if they’re going to panic, it should be about the vaccines, for they are what are producing the variants that we’re supposed to be panicking about. From Joseph Mercola at lewrockwell.com:

The inevitable is now here. Another SARS-CoV-2 variant dubbed Omicron has reportedly arisen in fully “vaccinated” patients in Botswana.1 Handfuls of cases have also emerged in other areas of the world. Judging by the doomsday headlines2 and government imposed lockdowns and border closings, the technocratic elite would really like everyone to panic about this one.

In response, Japan, Israel and Morocco immediately closed their borders to all foreign travelers. The U.S., the U.K., Canada and the European Union banned travelers from southern Africa specifically. Australia delayed its reopening plans and China announced a “zero-tolerance approach” to the new variant.3 But is the fear justified? Probably not.

While the Omicron variant appears to spread more rapidly than previous mutations, and affects people younger than 40 to a greater degree than before, there’s no evidence that it has a higher lethality. On the contrary, it may actually be milder.

That seems to be the opinion of Dr. Angelique Coetzee, chair of the South African Medical Association, who discovered the Omicron variant, who in a recent interview (see video above) said:4

“Looking at the mildness of the symptoms that we are seeing — apparently, there’s no reason for panicking as we don’t see severely ill patients… The most predominant complaint is severe fatigue for one or two days, with headache, body aches and pain.

Some will have a scratchy throat and some will have a dry cough [that] comes and goes. Those are more or less the big symptoms we have seen.”

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From an immunological point of view, boosters and mass vaccination are as harmful as mold on a wall, by Geert Vanden Bossche

The vaccines and boosters are worse than useless, they’re dangerous. From Geert Vanden Bossche at voiceforscienceandsolidarity.org:

From an immunological point of view, boosters and mass vaccination in general are as harmful as mold on a wall.

The vaccine can not prevent infection nor transmission. By again increasing the antibodies (with the booster), the virus is put under an even higher immune pressure while further expanding its capacity to escape from the vaccinal antibodies (Abs). As a result more infectious variants gain a competitive advantage and hence, will spread stronger amongst the population. This only precipiates and expands the evolutionary capacity of the virus to resist the vaccines. The level of protection WHO has recently been claiming (40%) is anything but due to the vaccines and can only be ascribed to some ‘trained’ innate immunity large parts of the population acquired prior to vaccination as a result of asymptomatic/ mild infection. It is crystal clear, indeed, that none of the C-19 vaccines is capable of blocking transmission, not even by 1 % ! Because vaccinal Abs suppress relevant innate Abs, these vaccines have no capacity whatsoever to confer sterilizing immunity. Consequently, none of these vaccines help to build herd immunity; on the contrary, they generate a breeding ground in vaccinees for more infectious variants, thereby further increasing infection rates and threatening both the unvaccinated and vaccinated. Moreover, vaccinal Abs tend to outcompete innate Abs for binding to SARS-CoV-2 because of their higher affinity for the virus. This particularly applies to naive innate Abs (children!) and already explains why C-19 vaccination is at risk of dramatically weakening people’s first line of immune defense, especially in children. Our innate immunity is not only well armed to protect against COVID-19 (including all its variants!), but also against a number of other viruses causing acute respiratory disease.

There can be no doubt, therefore, that such an assault of our immune system will have dramatic consequences on both individual and public health. Basically, mass vaccination is now turning Covid-19 into a disease of young and healthy unvaccinated people while enabling the virus to break through both the innate and adaptive immune defense of vaccinees due to vaccine-mediated suppression of innate Abs and viral resistance to vaccinal Abs, respectively. For those who didn’t get it thus far, Omicron will repeat that lesson; its teaching will only be a bit tougher and will soon silence all those who are trying to convince their people that they can outsmart the virus and, as they ridiculously claim, ‘stay ahead of the virus’.

https://www.voiceforscienceandsolidarity.org/scientific-blog/from-an-immunological-point-of-view-boosters-and-mass-vaccination-are-as-harmful-as-mold-on-a-wall

Vaccination  Causes Covid Variants, by Paul Craig Roberts

The process is called immune escape, and warnings came early on from among others Geert Vanden Bossche. This is apparently what is happening. From Paul Craig Roberts at paulcraigroberts.org:

https://undercurrents723949620.wordpress.com/2021/07/20/the-unvaccinated-are-not-fueling-covid-variants/

‘Super mutant’ Covid strain triggers emergency response

https://www.rt.com/news/541363-mutant-covid-who-emergency/

These “mutant strains” or variants are produced in response to the Covid vaccine. In other words, Fauci, Big Pharma, the medical establishment, and dumbshit politicians have unleashed an ever changing virus upon the world. The only hope is to immediately stop all Covid vaccination.

The Covid vaccinated are a grave threat to the unvaccinated, not only because the vaccinated “shed” the virus, thus spreading the virus to others, but also because the vaccine enables the virus to mutate in order to escape an immune response. The immunity the mutated variant of the virus achieves from the vaccine also gives the virus protection against the innate human immune system. In other words, people who have not damaged their innate immune system by taking the vaccine could now be confronted with a variant that their immune system is less able to repel.

What Fauci has done by financing the creation of the Covid-19 virus and by walking Big Pharma’s “vaccine” through the emergency use process is to create a Frankenstein virus capable of escaping immune responses.

How bad for humanity this turns out to be remains to be seen. What we do know is the more people are vaccinated, the worse it will be. All Covid vaccination should be stopped immediately before damage to the immune system makes more people susceptible to illnesses and death.

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Why are the current Covid-19 mass vaccinations to be considered a public health experiment, by Geert Vanden Bossche

Read this one carefully because the implications are quite disturbing. From Geert Vanden Bossche at geertvandenbossche.org:

Why are the current Covid-19 mass vaccinations to be considered a public health experiment of international concern?

First, there is no precedent to the use of non-replicating viral vaccines in mass vaccination campaigns conducted during a pandemic, or even epidemic, of a highly mutable virus. The challenge of such an undertaking becomes even more difficult as more infectious antigenic variants had already been circulating by the time the first mass vaccination campaigns were initiated (i.e., Alpha, Beta, and Gamma variants). Their spread was featured by distinct temporal and geographic patterns, the underlying mechanism of which was not understood. Prior to the start of this universal vaccination program no single publication existed that came even close to suggesting that mass vaccinations using vaccines that permit transmission could be successful in extinguishing a pandemic of a highly mutable virus. No such publication exists to this day, and the idea becomes even more preposterous when considering several infectious variants had already expanded in prevalence by the time the vaccines were rolled out. There is ample evidence from similarly highly mutable RNA viruses like Influenza virus and Enterovirus that expansion in prevalence of antigenic variants is driven by selective immune pressure on viral infectiousness exerted by antibodies, and that antigenic variation diminishes or even abolishes the protective neutralization capacity of Influenza virus or Enterovirus vaccines directed at a specific antigenic lineage (1, 2). Consequently, nonreplicating monovalent enteroviral vaccines, for example, are only used at scale in vaccination campaigns of vulnerable target groups (e.g., children) deployed to fight recurrent epidemics of life-threatening enterovirus infection (e.g., EV-A71) in the Asia Pacific region (3). Interestingly, the US FDA did not approve these vaccines due to ‘concerns about the effectiveness against different pandemic strains, safety, and quality control of vaccine production’ (3).

Mass vaccination programs previously conducted to combat viral epidemics/pandemics (e.g., smallpox, polio, measles, yellow fever) have nothing in common with the ongoing mass vaccination campaigns today as those viruses are very different in terms of their pathogenesis, transmissibility, route of infection, potential reservoirs, predominant effector mechanisms involved in antiviral immunity, susceptibility of population segments, as well as with regard to the vaccines used (all prior vaccination campaigns involved live-attenuated virus).

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What happens if Israel fails the stress test? By Geert Vanden Bossche

The jury is still out on whether repeated booster shots will make the Covid outbreak better or worse. From Geert Vanden Bossche at geertvandenbossche.com:

Israel got an early start on vaccinating its population and began offering a third dose of mRNA vaccine in July to the older age group (≥ 60 years). The results from an observational study comparing the clinical outcome of participants who received a third shot to those in the same age group who had received only two shots over the same period clearly indicated that the risk of severe disease dropped by a factor of almost 20. Additionally, those who received the third dose were also enjoying some level of protection against infection as they were also less likely to test positive for SARS-CoV-2 (1).

These are strong results, and at first glance many of those within this age group and not yet boosted might feel ashamed for their indifference in protecting themselves and others! However, there is a catch, and it’s not about potential biases in the analysis of the study results, or criticism from a public health perspective of delivering additional shots to individuals while many others have not even had their first.

The caveat is much more fundamental and has to do with immunology: a discipline that seems to have been largely reduced since the crisis began to measuring antibodies (Abs) in the blood. The results above were obtained after a very short observation period (12 days), and there is no data yet on the long-term outcome of repeated booster immunizations. This prompts an interesting question: could the immune-protective effect observed within 2 weeks of a booster injection trigger a short-term replenishment of the ‘lost’ protection against infection while at the same time not translating into long-term protection against infection or disease? The answer is most definitely ‘yes’ and can only be understood if one brings into play the single most important confounder of all Covid-19 vaccine efficacy studies conducted thus far: innate immunity. It is well known that, regardless of any induced antigen (Ag)-specific adaptive immune response, all vaccines (including mRNA vaccines) have an adjuvant effect: they stimulate innate immune effectors, some of which have antiviral activity and/or facilitate adaptive immunity (2, 3, 4). Without going into mechanistic detail, there is no doubt that some of these innate, nonAg-specific immune responses have a short-lived antiviral effect. This could already explain why booster doses in the population described above can prevent viral infection while recalling anti-spike Abs. It may also be tempting to assume that these recalled Abs are now responsible for enhanced protection from both infection and disease. However, from an immunological viewpoint, it is difficult to understand how a rapid recall of the very same anti-S Abs in a previously vaccine-primed population would now all of a sudden enable better protection from infection and disease. If innate immunity is indeed the confounder, then the outcome of long-term surveillance studies would look very different. Given the more potent neutralizing Abs booster shots are generating against variants (5), the S(pike)-directed immune pressure in the population will only continue to rise while still failing to curtail the spread of the predominantly circulating highly infectious SARS-CoV-2 variant (e.g., Delta variant). On the contrary, it would be reasonable to assume that upon an additional booster shot the more potent Abs further contribute to selecting S-directed immune escape variants and, therefore, turn the previously primed population in an even more fertile breeding ground for the highly infectious Delta variant. As vaccine-elicited Ab responses have a much longer duration (and can be memorized) than that induced by short-term innate immune activation, and as vaccinal Abs suppress the functional capacity of pre-existing CoV-reactive innate Abs, short-term vaccine-mediated innate immune protection against viral infection or disease does not automatically imply a positive effect of the vaccine on viral infection or morbidity rates in the longer term. Interpretations from scientists who only conduct short-term surveillance studies in vaccinees, the majority of whom are adults or elderly, lead to erroneous, although peer-reviewed conclusions such as: ‘Although vaccines are less effective against asymptomatic disease (*) or against transmission than against severe disease, even in populations with fairly high vaccination rates the unvaccinated are still the major drivers of transmission and are themselves at the highest risk of serious disease’ (6). This clearly illustrates their lack of understanding of the contribution of innate immunity in providing short-term protection after vaccination, and in the more durable protection of young and healthy unvaccinated age groups.

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Keep looking at snapshots and you’ll never see where this pandemic is headed . . . until it reaches its final destination, by Geert Vanden Bossche

The Covid vaccines are making the pandemic worse, not better. From Geert Vanden Bossche at geertvandenbossche.org:

The debate and tension over the efficacy of the Covid-19 vaccines is flaring up. Comparative assessments of vaccine-mediated protection from infection, disease, hospitalization, and death in vaccinated and unvaccinated people are all over the place, with results ranging from convincing evidence of benefit to compelling proof of failure depending on the source of information. Those who’ve become addicted to these comparative statistics seem to forget that gauging the success of human intervention in a pandemic is about measuring success in a dynamic phenomenon, and that snapshots taken under certain conditions/settings do not provide information about the overall evolutionary trend and likely health outcome of a pandemic. The latter can only be monitored by measuring temporal changes of parameters that are relevant to public and individual health.

By March 2021, molecular epidemiologists had already expressed their concern about the emergence of a super-variant that ‘might have any combinations of increased transmissibility, altered virulence and/or increased capacity to escape population immunity’ and would, therefore, enjoy a huge fitness advantage (1). Back then, their concern was based on phylogenetics-based natural selection analysis indicating that immunity-mediated selective pressure is driving convergent evolution of a diversified spectrum of mutations to ensure viral persistence in the face of mounting infectious and vaccine-induced host immune pressure.

Their findings lead one to conclude that mass vaccination in the presence of more infectious variants inevitably involves selection-driven convergence of compensatory adaptive mutations at positively selected genome sites, and hence promotes enhanced expansion in prevalence of more transmissible immune escape variants. This would imply that vaccine efficacy is expected to diminish over time while the infection rate would progressively increase. It is reasonable to assume that the evolutionary convergence of more infectious immune escape variants and the culmination thereof into a ‘super-variant’ will also cause distinct trajectories of the pandemic to increasingly converge in countries/regions that are subject to mass vaccination.

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The unforgivable sin, by Geert Vanden Bossche

We’re inflicting the manifest risks of Covid vaccinations on a group who has almost no chance of getting Covid—children. That’s unforgivable. From Geert Vanden Bossche at geertvandenbossche.org:

One wonders how it is possible that while it has now been reported that vaccinated shed and transmit as much virus as unvaccinated people (1), the vaccinated are still protected against severe disease whereas the unvaccinated are said to be unprotected. So, how can one explain that viral shedding and transmission and hence, viral replication no longer seem to be impacted by the vaccine whereas the opposite still applies to the occurrence of (severe) disease?

Based on their study results, the authors from the above-mentioned report (1) conclude that there is no significant difference in viral load between groups of vaccinated and unvaccinated, asymptomatic and symptomatic people who became infected with SARS-CoV-2 Delta variant. So, again: Considering that vaccinees shed and transmit as much virus as unvaccinated people, how could one even postulate that unvaccinated people are susceptible to severe disease whereas vaccinees are still largely protected from severe disease?

Frankly speaking, this doesn’t make any sense at all. So there must be a ‘small’ detail the current ‘narrative’ overlooked.

Wait a minute … Does the above-mentioned comparison of viral load between the vaccinated and the unvaccinated include people who contracted SEVERE disease? It didn’t! So, could it be that the unvaccinated are only susceptible to severe disease when their first (i.e., innate) line of immune defense is weakened because of a lowered functional capacity of their innate, poly-reactive antibodies (Abs)? Hmmm, this could definitely explain why elderly people and those who’re immune suppressed or have underlying diseases are susceptible to severe Covid-19 disease. But what about our healthy youngsters and children as these age groups are thought to have excellent innate, pre-existing immune effector cells (2) but are now also increasingly contracting severe Covid-19 disease. Could this be due to spike(S)-specific Abs that young and healthy children may harbor for up to 8 weeks after they contracted asymptomatic infection and that outcompete their innate protective Abs (3)? If this is true, this would imply that only a small part of young and unvaccinated people are susceptible to severe disease (i.e., those who get quite rapidly re-exposed to Sars-CoV-2 after previous infection) but that the vast majority of them are still protected from severe disease, regardless of which Sars-CoV-2 lineage is predominant in the circulating viral population. This seems, indeed, to be the case! Or do some of our ‘experts’ believe that the unvaccinated children and youngsters who don’t get Covid-19 disease have simply not been exposed to the virus at all? But how could that happen given the fact that in most countries the pandemic started over 1.5 years ago and that we’re now dealing with highly infectious variants and that infection prevention measures have largely been relaxed?

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Stop Mass Vaccination Now! by Raúl Ilargi Meijer

They’re not safe; they’re not effective; they’re making the situation worse. From Raúl Ilargi Meijer at theautomaticearth.com:

We’ve been saying this for months now, in many variations, but the mass vaxx programs just continue. And that has to stop. We need to save lives not take them. And yes, the vaxxers have managed to propagandize -almost- everyone into believing the exact opposite of what is happening: you now believe that mRNA substances save lives.

Problem may be that they do, but only for a few weeks or months, and then you need another booster, while in the meantime, your body is filling up with cytotoxic spike proteins. The vaccines don’t kill the virus, they leave it alive while enhancing your body’s protection against it a bit, and for a short time.

Whether that means you should label them “non-sterilizing vaccines” or not vaccines at all is something I get tired of discussing, because that merely distracts from the main issue: these things have not been properly tested while they’re very invasive and long-lasting, and therefore potentially very dangerous.

One of the biggest dangers is that they trigger the virus into mutating. That’s what “non-sterilizing vaccines” do. Months ago, Geert VandenBossche started warning about this, many other doctors and medical specialists have followed, but they all get banned and deleted and censored. Never state the obvious!

Perhaps the No. 1 peril behind mRNA substances is something many of the same doctors warn about, an emerging auto-immune disease called antibody-dependent enhancement (ADE), which emerged through years of trials of these same substances in labs and animal tests, all of which were conveniently stricken from the propaganda record. But they still exist.

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C-19 Pandemia: Quo vadis, homo sapiens? by Geert Vanden Bossche

How a mass vaccination program against a virus can leave a population much sicker, from Geert Vanden Bossche at geertvandenbossche.org:

1. Summary:

The WHO’s mass vaccination program has been installed in response to a public health emergency of international concern. As of the early days of the mass vaccination campaigns, at least a few experts have been warning against the catastrophic impact such a program could have on global and individual health. Mass vaccination in the middle of a pandemic is prone to promoting selection and adaptation of immune escape variants that are featured by increasing infectiousness and resistance to spike protein (S)-directed antibodies (Abs), thereby diminishing protection in vaccinees and threatening the unvaccinated. This already explains why the WHO’s mass vaccination program is not only unable to generate herd immunity (HI) but even leads to substantial erosion of the population’s immune protective capacity. As the ongoing universal mass vaccination program will soon promote dominant propagation of highly infectious, neutralization escape mutants (i.e., so-called ‘S Ab-resistant variants’), naturally acquired, or vaccinal neutralizing Abs, will, indeed, no longer offer any protection to immunized individuals whereas high infectious pressure will continue to suppress the innate immune defense system of the nonvaccinated. This is to say that every further increase in vaccine coverage rates will further contribute to forcing the virus into resistance to neutralizing, S-specific Abs. Increased viral infectivity, combined with evasion from antiviral immunity, will inevitably result in an additional toll taken on human health and human lives. Immediate action needs, therefore, to be taken in order to dramatically reduce viral infectivity rates and to prevent selected immune escape variants from rapidly spreading through the entire population, whether vaccinated or not. This first critical step can only be achieved by calling an immediate halt to the mass vaccination program and replacing it by widespread use of antiviral chemoprophylactics while dedicating massive public health resources to scaling early multidrug treaments of Covid-19 disease.

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Our Species Is Enduring Largest Uncontrolled Experiment Ever, We Shouldn’t Ignore Vanden Bossche’s Warning, by Children’s Health Defense

Those who take one of the vaccines are guinea pigs in a giant experiment. Here’s hoping it turn out okay for them. If it doesn’t, the experimenters can’t be sued. From Children’s Health Defense at lewrockwell.com:

In his latest piece on the controversy stirred up by Geert Vanden Bossche, Alliance for Natural Health International’s Rob Verkerk, Ph.D., says to ignore Vanden Bossche’s warning would be “foolhardy and inconsistent with the known science.”

EDITOR’S NOTE: The Defender is committed to providing a space for scientific debate. This is an opinion piece by Rob Verkerk, Ph.D., on concerns raised by Geert Vanden Bossche, Ph.D. about immune escape and mass vaccination during a pandemic. This article follows Verkerk’s recent interview and previous analysis of the ongoing debate (this piece + this piece) sparked by Vanden Bossche.

It was a week ago that we released my interview with Geert Vanden Bossche on our brand new Speaking Naturally channel. It’s caused something of a stir in some circles. Mainly among those of us who don’t see vaccines as a panacea or at least the sole exit strategy to exit lockdowns, social distancing and other elements of the surrealism that have swept the world since the genome of a virus causing pneumonia-like symptoms in China was sequenced last January.

The silence from those who are overseeing or administering the global mass vaccination program has been deafening.

Some of the scientific concerns around Geert Vanden Bossche’s arguments appear to be the result of linguistic interpretations. Others challenge Geert’s speculative concerns linked to immune escape through the application of selection pressure from vaccines that could create ever more vaccine resistant, and potentially dangerous, virus variants.

For the uninitiated, “immune escape” is a term used to describe when the host (in this case humans) is no longer able to recognize and counter (eliminate or sterilize) a pathogen (in this case, a relevant variant or mutant of SARS-CoV-2).

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